(Boston, Mass.) – Researchers led by Isabel Beerman of the Departmentof Stem Cell and Regenerative Biology at Harvard have demonstrated that quiescent hematopoietic stem cells accumulate DNA damage over time. This contradicts previously held assumptions that some blood stem cells in the bone marrow stay quiescent (i.e. do not divide) for long periods of time in order to avoid DNA damage.
Quiescent HSCs Shown to Accumulate DNA Damage
